What it entails:
SPECT/CT, or Nuclear Medicine scanning is a hybrid imaging technique that combines functional imaging from SPECT with anatomical imaging from CT.
Before a SPECT/CT scan, the patient receives an intravenous injection or swallows a small dose of radiotracer. Various radiotracers are used to diagnose and evaluate different conditions such as bone/joint diseases, cancer, endocrinological, bowel, kidney or biliary diseases.
The patient lies on a table that moves through a donut-shaped machine called a SPECT/CT scanner. This scanner has two components: one to detect location and intensity of SPECT tracer in the body, and one to emit and detect x-ray beams from different angles around the body. Computer processing of this information allows detailed images to be generated.
SPECT/CT is a powerful diagnostic tool that provides valuable insights into a wide range of medical conditions, aiding in early detection, accurate diagnosis, and effective treatment planning.
Benefits of SPECT/CT:
- Comprehensive Imaging: SPECT/CT provides both anatomical and functional information. The CT component offers detailed images of the body's tissues and organs, while the SPECT component demonstrates tissue and organ function, highlighting areas of abnormal activity.
- Enhanced Diagnostic Accuracy: SPECT assists in distinguishing normal uptake from sites of disease, improving the accuracy of diagnosis. The CT component provides detailed anatomical information, allowing precise localisation of functional abnormalities detected by SPECT. This is particularly useful in areas with complex anatomy.
- Versatility: SPECT can image a wide range of processes in the body, depending on the radiotracer used:
- Orthopaedics: SPECT/CT is useful in evaluating bone and joint disorders, such as fractures, infections, and prosthetic complications, by providing detailed anatomical and functional information.
- Oncology: SPECT/CT is used in oncology for tumour detection, staging, and treatment monitoring. It can differentiate between cancerous lesions and normal tissue and evaluate the response to therapy.
- Endocrinology: SPECT/CT is used to diagnose conditions causing abnormal function of the thyroid and parathyroid glands.
- Urology: SPECT/CT is used to diagnose conditions causing urinary tract obstruction and postinfectious scarring of the kidneys.
- Gastroenterology: SPECT/CT is used to diagnose diseases of the bile ducts, gallbladder, stomach and bowel.
- Cardiology: SPECT/CT allows assessment of blood flow in the heart, which is used in diagnosing coronary artery disease and planning interventions.
- Neurology: SPECT/CT assists in diagnosing neurological conditions, such as Parkinson's disease and dementia, by mapping functional abnormalities in the brain.
- Personalised Treatment Planning: SPECT/CT is used in theranostics, where it helps in both diagnosing diseases and planning targeted therapies, such as in radionuclide therapy.